ABSTRACT
Significant risks to human health are posed by the 2019 coronavirus illness (COVID-19). SARS coronavirus type 2 receptor, also known as the major enzyme in the renin-angiotensin system (RAS), angiotensin-converting enzyme 2 (ACE-2), connects COVID-19 and RAS. This study was conducted with the intention of determining whether or not RAS gene polymorphisms and ACE-2 (G8790A) play a part in the process of predicting susceptibility to infection with COVID-19. In this study 127 participants, 67 of whom were deemed by a physician to be in a severe state of illness, and 60 of whom were categorized as "healthy controls".The genetic study included an extraction of genomic DNA from blood samples of each covid 19 patients and healthy controls, then amplification the site of SNP (rs2285666) Within the ACE2 gene by using specific primers, sequencing PCR products, and genotyping to detect the role of the ACE-2 gene (rs2285666) in the incidence of COVID-19. ACE-2 (rs2285666) is statistically associated to COVID-19. The COVID-19 group had 65.67 %of individuals with the wild-type homozygous genotype (GG) and 20% in the control group, while the control group had 63.33% of individuals with the mutant genotype (AA). Consequently, the wild-type homozygous (GG) and allele (G) may be considered a risk factor (etiological fraction E. F) for COVID-19 in Iraqi patients, whereas the mutant homozygous (AA) and allele (A) may be considered a protective factor (preventive fraction). The findings of the present study reveal that carriers of the GG genotype of ACE2 (rs2285666) are substantially more susceptible to COVID-19.Copyright © 2023 Allami et al.
ABSTRACT
Corresponding to the current pandemic issue, Covid-19 has driven unprecedented economic loss and instability to many, particularly among low-income families, especially in Asia. In context, families involved single mothers who are markedly affected by job loss;thus, low-income households had markedly affected the well-being and development of children. In addition to family environment, sociodemographic variables, such as socioeconomic status, educational level of parents, and parental conflict, had also been associated with problematic or competent behaviors during childhood. This scoping review aimed to determine current knowledge regarding the impact of single motherhood on the emotional well-being of a child. This review was reported in accordance with the guidelines of the Preferred Reporting Items for Systematic reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Three databases, namely Scopus, Web of Science, and Education Resources Information Center (ERIC), were used for data scoping. A total of 341 studies were identified, but only 15 studies conducted in the Asian continent were eligible for selection. Results showed five significant findings concerning parent-child dysfunctional interaction, time spent, family socioeconomic status, parenting skills, and parental styles that impacted the emotional well-being of children, causing child development delay and delinquency.
ABSTRACT
Living in a world of unstable and fluctuating economy has put children’s development at risk particularly children from low-income families. Hence their development should be on alert. The concern regarding online learning is crucial towards children’s emotional development as it can positively or negatively affect them. In the volatility, uncertainty, complexity, and ambiguity (VUCA), no other performance is relevant due to high-speed change. Children as young generations today have more disruptive behaviours causing adults to be fearful in dealing with their unruly behaviour. This study discovered the impact of the current environmental situation of uncertainty and parent-child relationship on children’s emotional development. In view of the COVID-19 pandemic restrictions and preventive measures, the study was conducted with parents’ consent using an online survey tool administered using Google Form. The quantitative survey comprised general population-CORE (GP-CORE) and perceived stress scale (PSS) questionnaires from 108 respondents studying in primary schools around urban areas in Selangor, Malaysia. The findings were analysed and described descriptively. Findings showed that children are greatly affected by parents’ job loss and low-income households’ instability, causing emotional stress when learning from home. Therefore, the study can be the mechanism to aid the educational system in emphasising emotional learning in school. © 2022, Intelektual Pustaka Media Utama. All rights reserved.
ABSTRACT
The plastic industry is one of the biggest and essential industries, ranging from domestic to engineering products. Nowadays, plastic waste is one of the major issues human-faced worldwide. It is predicted to worsen due to the increment in online purchasing rising from the Covid-19 situations. On the other hand, the construction industry is the largest industry in different economies and the highest consumer of raw materials. Along with the growing demand for concrete aggregates, natural stone materials are overused and eventually deplete resources. Both severe problems can be mitigated by recycling these plastic wastes to serve as an alternative to aggregates in concrete. Despite accumulative efforts, the produced plastic waste aggregates (PWA) is still inferior in strengthening the concrete due to poor interaction between both particles. Therefore, steps to further improving their properties and compatibility with concrete through various approaches are crucial. This review briefly introduces the current situation of concrete industries and global plastic waste accumulation issues. The efforts in the utilization of plastic waste aggregates in concrete alongside their properties are also discussed. Lastly, the water-assisted melt compounding and advantages in the processing of thermoplastic composites are also presented to serve as the platform for a new processing approach to be utilized in PWA production. Therefore, a better insight into the potential of producing PWA with improved physical, mechanical properties corresponds to the enhancing concrete strength via water-assisted melt compounding is offered. © 2022, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.